N6AMT1

This gene encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jul 2014]

Description

N-6 adenine-specific DNA methyltransferase 1

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Centrosome

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

21 (28872191 - 28885371)

Ensembl ID

ENSG00000156239  (ver. 103.38)

Orthologs

Mouse N6amt1: ENSMUSG00000044442

UniProt

Q9Y5N5

neXtProt

NX_Q9Y5N5

Human splice variants
Mouse splice variants

Protein structure