FNab07295

antibody from FineTest Biotech

Targeting: RIC8A synembryn, synembryn-A

Western blot

ELISA

Immunohistochemistry

Antibody data

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Validation data

Product number: FNab07295 - Provider product page
Provider: FineTest Biotech
Product name: RIC8A antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Guanine nucleotide exchange factor(GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex(By similarity). Also acts as an activator for G(q)-alpha(GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: resistance to inhibitors of choline sterase 8 homolog A(C. elegans)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

RIC8A protein structure - FNab07295 shown in red.