CABT-B12266

antibody from Creative Diagnostics

Targeting: BTN3A1 BT3.1, BTF5, BTN3.1, CD277

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-B12266

Provider

Creative Diagnostics

Product name

Mouse anti-Human BTN3A1 monoclonal antibody, clone CU4.2 [PE]

Antibody type

Monoclonal

Description

It recognozes the human CD277 antigen, a single-pass type I membrane protein, which is also known as butyrophilin subfamily 3 member A1 (BTN3A1). CD277 belongs to the B7 family members and is expressed in various immune cells such as T cells, B cells, monocytes, NK cells, dendritic cells, a subset of stem cells, and endothelial cells. It is also consistently expressed in stromal and some tumor cells. CD277 triggering considerably enhances T cell receptor (TCR) induced cytokine production and cell proliferation. It mediates the response of T cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

Reactivity

Human

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG