FOLH1

gene product
FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]
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448 antibodies from 24 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
28 antibodies
OriGene
6 antibodies
Atlas Antibodies
1 antibody
antibodies-online
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Aviva Systems Biology
12 antibodies
Acris Antibodies GmbH
24 antibodies
R&D Systems
10 antibodies
Thermo Fisher Scientific Pierce
6 antibodies
GeneTex
17 antibodies
Abnova Corporation
16 antibodies
LifeSpan BioSciences, Inc.
66 antibodies
Proteintech Group
1 antibody
Biorbyt
13 antibodies
Cell Signaling Technology, Inc
2 antibodies
RabMAbs
6 antibodies
Creative Biomart
53 antibodies
BioLegend
13 antibodies
RayBiotech, Inc.
6 antibodies
GenWay
2 antibodies
United States Biological
26 antibodies
Spring Bioscience
8 antibodies
Abgent
1 antibody
EMD Millipore
2 antibodies
Sigma-Aldrich
2 antibodies