Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
IL17RA
Interleukin 17 receptor ACD217, CDw217, hIL-17R, IL-17RA, IL17R
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]
Top validated antibodies |
|||||
| GeneTex |  GTX16598 |
1 references | Polyclonal |
WB
EL
ICC
IHC
|
|
| R&D Systems | MAB177-100 |
12 references | Monoclonal |
WB
FC
BN
|
|
| Novus Biologicals | AF177 |
9 references | Polyclonal |
WB
FC
BN
|
|
| LSBio | LS-C201107 |
Polyclonal |
WB
EL
ICC
IHC
|
||
| Invitrogen Antibodies | PA5-34571 |
1 references | Polyclonal |
WB
IHC
OA
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider