Tissue expression
Cell line expression
Protein structure
PIDD1
P53-induced death domain protein 1DKFZp434D229, LRDD, MGC16925, PIDD
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Top validated antibodies |
|||||
Proteintech Group | 12119-1-AP | 2 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 12119-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
||
NovoPro Bioscience Inc. | 112317 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
Enzo Life Sciences | ALX-804-837-C100 | 3 references | Monoclonal |
WB
ICC
IHC
|
|
FineTest Biotech | FNab04842 | Polyclonal |
WB
EL
ICC
IP
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider