11-6006-25

antibody from ABEOMICS Inc.
Targeting: RNF31 FLJ10111, FLJ23501, HOIP, Paul, ZIBRA
Provider product page for 11-6006-25

Antibody data

Product number
11-6006-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-HOIP/RNF31 Antibody
Antibody type
Polyclonal
Description
RNF31 (ring finger protein 31), also known as HOIP (HOIL-1-interacting protein) is an atypical E3 ubiquitin ligase that belongs to the RBR (RING-between-RING) family of E3 ligases and is the catalytic component of LUBAC (linear ubiquitin chain assembly complex), a multisubunit E3 ligase. Linear ubiquitin chains are assembled by the LUBAC (Linear Ubiquitin Chain Assembly Complex), which plays a critical role in the activation of the NF-kappaB pathway that is involved in various functions, including cell survival and inflammation. RNF31 is essential for the assembly and function of LUBAC and for various processes governing inflammation and immunity in both hematopoietic and nonhematopoietic cells.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant HOIP/R
NF31 protein (amino acids 780-1020)
was used as the immunogen for this
antibody.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
RNF31 protein structure - 11-6006-25 shown in red.