FBXL16

Members of the F-box protein family, such as FBXL16, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]). [supplied by OMIM, Mar 2008]

Description

F-box and leucine-rich repeat protein 16

Protein family

Mapped to UniProt SWISS-PROT, Protein evidence (Kim et al 2014)

Chromosome

16:p13.3 (692498 - 705829)

Ensembl ID

ENSG00000127585  (ver. 77.38)

Orthologs

Mouse Fbxl16: ENSMUSG00000025738

UniProt

Q8N461

neXtProt

NX_Q8N461

Human splice variants
Mouse splice variants