Tissue expression
Cell line expression
Protein structure
EIF2AK4
Eukaryotic translation initiation factor 2 alpha kinase 4GCN2, KIAA1338
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]
Top validated antibodies |
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Antibodies.com | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Monoclonal |
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Novus Biologicals | ![]() |
Monoclonal |
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