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SIGLEC5
Sialic acid binding Ig like lectin 5CD170, CD33L2, OB-BP2, SIGLEC-5
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
Top validated antibodies |
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| R&D Systems |  AF1072 |
4 references | Polyclonal |
WB
IHC
FC
BN
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| Novus Biologicals | AF1072 |
4 references | Polyclonal |
WB
IHC
FC
BN
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| Invitrogen Antibodies | PA5-47058 |
1 references | Polyclonal |
IHC
FC
OA
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| Boster Biological Technology | M06510 |
Monoclonal |
EL
ICC
IP
IHC
FC
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| Abnova Corporation | PAB3634 |
3 references | Polyclonal |
WB
IHC
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