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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- MAB2290 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2290, RRID:AB_1715783
- Product name
- THOP1 monoclonal antibody, clone 4D6
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against synthetic peptide of THOP1.
- Isotype
- IgG
- Antibody clone number
- 4D6
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation.
Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase.
Monoclonal antibodies against the human metalloprotease EC 3.4.24.15 label neurofibrillary tangles in Alzheimer's disease brain.
York IA, Mo AX, Lemerise K, Zeng W, Shen Y, Abraham CR, Saric T, Goldberg AL, Rock KL
Immunity 2003 Mar;18(3):429-40
Immunity 2003 Mar;18(3):429-40
Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase.
Saric T, Beninga J, Graef CI, Akopian TN, Rock KL, Goldberg AL
The Journal of biological chemistry 2001 Sep 28;276(39):36474-81
The Journal of biological chemistry 2001 Sep 28;276(39):36474-81
Monoclonal antibodies against the human metalloprotease EC 3.4.24.15 label neurofibrillary tangles in Alzheimer's disease brain.
Conn KJ, Pietropaolo M, Ju ST, Abraham CR
Journal of neurochemistry 1996 May;66(5):2011-8
Journal of neurochemistry 1996 May;66(5):2011-8
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of THOP1 in HeLa whole cell lysate (30 ug) (Lane 1 : 0.5 ug/mL ; Lane 2 : 2 ug/mL) with THOP1 monoclonal antibody, clone 4D6 (Cat # MAB2290).
