BS6608

antibody from Bioworld Technology, Inc
Targeting: FKBP1A FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE
Provider product page for BS6608
Western blot
Immunohistochemistry

Antibody data

Product number
BS6608 - Provider product page
Provider
Bioworld Technology, Inc
Product name
FKBP1A polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human FKBP1A.
Description
Immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases which bind to and mediate the effects of immunosuppressive drugs such as Cyclosporin, FK506 and Rapamycin. The prototypic member of the family, FKBP12, was originally identified as a target of FK506 and Rapamycin activity. FKBP12 is an abundant, evolutionarily conserved cytoplasmic protein. Although the molecular role of FKBP12 activity is not well understood, the protein has been implicated as a regulator of diverse array of cellular processes including T cell activation, entry into the cell cycle and intracellular calcium release. Interestingly, FKBP12 has been shown to associate with the intracellular cytoplasmic domain of the type I TGFÉÇ receptor. This association is constitutive and not dependent on the activation of the receptor.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
FKBP1A protein structure - BS6608 shown in red.