FNab06377

antibody from FineTest Biotech
Targeting: EGLN3 HIFPH3, PHD3
Provider product page for FNab06377
Western blot
ELISA
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
FNab06377 - Provider product page
Provider
FineTest Biotech
Product name
PHD3 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
EGLN3, also named as HPH-1, HIF-PH3, HPH-3 and PHD3, is a cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor(HIF) alpha proteins. It hydroxylates a specific proline found in each of the oxygen-dependent degradation(ODD) domains(N-terminal, NODD, and C-terminal, CODD) of HIF1A. It is a regulator of cardiomyocyte and neuronal apoptosis. EGLN3 can be a prognostic marker for gastric cancer.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
egl nine homolog 3
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
EGLN3 protein structure - FNab06377 shown in red.