FNab08592

antibody from FineTest Biotech

Targeting: TELO2 hCLK2, KIAA0683, TEL2

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Validation data

Product number: FNab08592 - Provider product page
Provider: FineTest Biotech
Product name: TELO2 antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: TEL2, telomere maintenance 2, homol og
Epitope: IgG2a
Isotype: IgG
Antibody clone number: 8B6
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

TELO2 protein structure - FNab08592 shown in red.