CARD6

This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008]

Description

Caspase recruitment domain family member 6

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

5 (40841308 - 40860175)

Ensembl ID

ENSG00000132357  (ver. 103.38)

Orthologs

Mouse Card6: ENSMUSG00000041849

UniProt

Q9BX69

neXtProt

NX_Q9BX69

Human splice variants
Mouse splice variants

Protein structure