Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN953691 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Nuclear Factor I/C (CCAAT-Binding Transcription Factor) (NFIC) (AA 179-208), (Middle Region) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 179-208aa) of human NFIC
- Description
- Purified through a Protein A column followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 179-208,Middle Region
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Nuclear Janus-activated kinase 2/nuclear factor 1-C2 suppresses tumorigenesis and epithelial-to-mesenchymal transition by repressing Forkhead box F1.
Identification of a region in the human IRS2 promoter essential for stress induced transcription depending on SP1, NFI binding and ERK activation in HepG2 cells.
Regulation of the CYP3A4 and CYP3A7 promoters by members of the nuclear factor I transcription factor family.
Nuclear factor I-C links platelet-derived growth factor and transforming growth factor beta1 signaling to skin wound healing progression.
Role of macrophage oxidative burst in the action of anthrax lethal toxin.
Nilsson J, Helou K, Kovács A, Bendahl PO, Bjursell G, Fernö M, Carlsson P, Kannius-Janson M
Cancer research 2010 Mar 1;70(5):2020-9
Cancer research 2010 Mar 1;70(5):2020-9
Identification of a region in the human IRS2 promoter essential for stress induced transcription depending on SP1, NFI binding and ERK activation in HepG2 cells.
Udelhoven M, Leeser U, Freude S, Hettich MM, Laudes M, Schnitker J, Krone W, Schubert M
Journal of molecular endocrinology 2010 Feb;44(2):99-113
Journal of molecular endocrinology 2010 Feb;44(2):99-113
Regulation of the CYP3A4 and CYP3A7 promoters by members of the nuclear factor I transcription factor family.
Riffel AK, Schuenemann E, Vyhlidal CA
Molecular pharmacology 2009 Nov;76(5):1104-14
Molecular pharmacology 2009 Nov;76(5):1104-14
Nuclear factor I-C links platelet-derived growth factor and transforming growth factor beta1 signaling to skin wound healing progression.
Plasari G, Calabrese A, Dusserre Y, Gronostajski RM, McNair A, Michalik L, Mermod N
Molecular and cellular biology 2009 Nov;29(22):6006-17
Molecular and cellular biology 2009 Nov;29(22):6006-17
Role of macrophage oxidative burst in the action of anthrax lethal toxin.
Hanna PC, Kruskal BA, Ezekowitz RA, Bloom BR, Collier RJ
Molecular medicine (Cambridge, Mass.) 1994 Nov;1(1):7-18
Molecular medicine (Cambridge, Mass.) 1994 Nov;1(1):7-18
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis in A549 cell line lysates (35ug/lane) using NFIC antibody Cat.-No. AP52861PU-N. This demonstrates this antibody detected the NFIC protein (arrow).