Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [2]
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Validation data
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- Product number
- AF1097 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal Endoglin/CD105 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human Endoglin in direct ELISAs and Western blots. In direct ELISAs, less than 15% cross-reactivity with recombinant mouse Endoglin and recombinant rat Endoglin is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references CD90 determined two subpopulations of glioma-associated mesenchymal stem cells with different roles in tumour progression.
A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression.
Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling.
Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers.
Novel Rat Model of Repetitive Portal Venous Embolization Mimicking Human Non-Cirrhotic Idiopathic Portal Hypertension.
Altered Biomarkers in Trophoblast Cells Obtained Noninvasively Prior to Clinical Manifestation of Perinatal Disease.
Evaluation of Nonperfused Retinal Vessels in Ischemic Retinopathy.
Automated Analysis and Classification of Histological Tissue Features by Multi-Dimensional Microscopic Molecular Profiling.
CD105 expression on CD34-negative spindle-shaped stromal cells of primary tumor is an unfavorable prognostic marker in early breast cancer patients.
Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction.
Key role of the endothelial TGF-β/ALK1/endoglin signaling pathway in humans and rodents pulmonary hypertension.
Expression of uPAR in tumor-associated stromal cells is associated with colorectal cancer patient prognosis: a TMA study.
Glyceryl trinitrate inhibits hypoxia-induced release of soluble fms-like tyrosine kinase-1 and endoglin from placental tissues.
Glial cell line-derived neurotrophic factor-secreting genetically modified human bone marrow-derived mesenchymal stem cells promote recovery in a rat model of Parkinson's disease.
Zhang Q, Yi DY, Xue BZ, Wen WW, Lu YP, Abdelmaksou A, Sun MX, Yuan DT, Zhao HY, Xiong NX, Xiang W, Fu P
Cell death & disease 2018 Oct 27;9(11):1101
Cell death & disease 2018 Oct 27;9(11):1101
A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression.
García-Hernández ML, Uribe-Uribe NO, Espinosa-González R, Kast WM, Khader SA, Rangel-Moreno J
Frontiers in immunology 2017;8:563
Frontiers in immunology 2017;8:563
Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling.
Jin Y, Muhl L, Burmakin M, Wang Y, Duchez AC, Betsholtz C, Arthur HM, Jakobsson L
Nature cell biology 2017 Jun;19(6):639-652
Nature cell biology 2017 Jun;19(6):639-652
Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers.
Moffett HF, Coon ME, Radtke S, Stephan SB, McKnight L, Lambert A, Stoddard BL, Kiem HP, Stephan MT
Nature communications 2017 Aug 30;8(1):389
Nature communications 2017 Aug 30;8(1):389
Novel Rat Model of Repetitive Portal Venous Embolization Mimicking Human Non-Cirrhotic Idiopathic Portal Hypertension.
Klein S, Hinüber C, Hittatiya K, Schierwagen R, Uschner FE, Strassburg CP, Fischer HP, Spengler U, Trebicka J
PloS one 2016;11(9):e0162144
PloS one 2016;11(9):e0162144
Altered Biomarkers in Trophoblast Cells Obtained Noninvasively Prior to Clinical Manifestation of Perinatal Disease.
Bolnick JM, Kohan-Ghadr HR, Fritz R, Bolnick AD, Kilburn BA, Diamond MP, Armant DR, Drewlo S
Scientific reports 2016 Sep 23;6:32382
Scientific reports 2016 Sep 23;6:32382
Evaluation of Nonperfused Retinal Vessels in Ischemic Retinopathy.
Powner MB, Sim DA, Zhu M, Nobre-Cardoso J, Jones R, Syed A, Chang AA, Keane PA, Tufail A, Egan CA, Fruttiger M
Investigative ophthalmology & visual science 2016 Sep 1;57(11):5031-5037
Investigative ophthalmology & visual science 2016 Sep 1;57(11):5031-5037
Automated Analysis and Classification of Histological Tissue Features by Multi-Dimensional Microscopic Molecular Profiling.
Riordan DP, Varma S, West RB, Brown PO
PloS one 2015;10(7):e0128975
PloS one 2015;10(7):e0128975
CD105 expression on CD34-negative spindle-shaped stromal cells of primary tumor is an unfavorable prognostic marker in early breast cancer patients.
Martinez LM, Labovsky V, Calcagno ML, Davies KM, Garcia Rivello H, Bianchi MS, Wernicke A, Fernández Vallone VB, Chasseing NA
PloS one 2015;10(3):e0121421
PloS one 2015;10(3):e0121421
Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction.
Kim J, Piao Y, Pak YK, Chung D, Han YM, Hong JS, Jun EJ, Shim JY, Choi J, Kim CJ
Stem cells and development 2015 Mar 1;24(5):575-86
Stem cells and development 2015 Mar 1;24(5):575-86
Key role of the endothelial TGF-β/ALK1/endoglin signaling pathway in humans and rodents pulmonary hypertension.
Gore B, Izikki M, Mercier O, Dewachter L, Fadel E, Humbert M, Dartevelle P, Simonneau G, Naeije R, Lebrin F, Eddahibi S
PloS one 2014;9(6):e100310
PloS one 2014;9(6):e100310
Expression of uPAR in tumor-associated stromal cells is associated with colorectal cancer patient prognosis: a TMA study.
Boonstra MC, Verbeek FP, Mazar AP, Prevoo HA, Kuppen PJ, van de Velde CJ, Vahrmeijer AL, Sier CF
BMC cancer 2014 Apr 17;14:269
BMC cancer 2014 Apr 17;14:269
Glyceryl trinitrate inhibits hypoxia-induced release of soluble fms-like tyrosine kinase-1 and endoglin from placental tissues.
Barsoum IB, Renaud SJ, Graham CH
The American journal of pathology 2011 Jun;178(6):2888-96
The American journal of pathology 2011 Jun;178(6):2888-96
Glial cell line-derived neurotrophic factor-secreting genetically modified human bone marrow-derived mesenchymal stem cells promote recovery in a rat model of Parkinson's disease.
Glavaski-Joksimovic A, Virag T, Mangatu TA, McGrogan M, Wang XS, Bohn MC
Journal of neuroscience research 2010 Sep;88(12):2669-81
Journal of neuroscience research 2010 Sep;88(12):2669-81
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human Endoglin/CD105 by Western Blot. Detection of Human Endoglin/CD105 by Western Blot.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human Endoglin/CD105 by Simple WesternTM. Detection of Human Endoglin/CD105 by Simple WesternTM.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Endoglin/CD105 in Mouse Kidney. Endoglin/CD105 in Mouse Kidney.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Endoglin/CD105 in Human Prostate. Endoglin/CD105 in Human Prostate.