DPABH-13102

antibody from Creative Diagnostics

Targeting: GHR GHBP

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

DPABH-13102

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-13102, RRID:AB_2512321

Product name

Rabbit Anti-Human GHR Polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.

Reactivity

Human, Porcine

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL