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antibody from antibodies-online
Targeting: CLEC7A
CD369, CLECSF12, dectin-1, hDectin-1, SCARE2
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN1449932 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) (Middle Region) antibody
- Antibody type
- Polyclonal
- Antigen
- 17 amino acid synthetic peptide near the center of Human CLEC7A
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Middle Region
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Syk-coupled C-type lectin receptors that mediate cellular activation via single tyrosine based activation motifs.
Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production.
Evolutionary analysis reveals collective properties and specificity in the C-type lectin and lectin-like domain superfamily.
The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages.
Kerrigan AM, Brown GD
Immunological reviews 2010 Mar;234(1):335-52
Immunological reviews 2010 Mar;234(1):335-52
Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production.
Underhill DM, Rossnagle E, Lowell CA, Simmons RM
Blood 2005 Oct 1;106(7):2543-50
Blood 2005 Oct 1;106(7):2543-50
Evolutionary analysis reveals collective properties and specificity in the C-type lectin and lectin-like domain superfamily.
Ebner S, Sharon N, Ben-Tal N
Proteins 2003 Oct 1;53(1):44-55
Proteins 2003 Oct 1;53(1):44-55
The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages.
Taylor PR, Brown GD, Reid DM, Willment JA, Martinez-Pomares L, Gordon S, Wong SY
Journal of immunology (Baltimore, Md. : 1950) 2002 Oct 1;169(7):3876-82
Journal of immunology (Baltimore, Md. : 1950) 2002 Oct 1;169(7):3876-82
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of CLEC7A in rat spleen tissue lysate with CLEC7A antibody Cat.-No AP55427PU-N at (A) 1 and (B) 2 μg/.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of CLEC7A in human spleen tissue with CLEC7A antibody Cat.-No AP55427PU-N at 5 μg/ml.
