Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB1059A-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human NKG2A/CD159a APC-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Recognizes the human NKG2A/CD94 heterodimer. It does not recognize the NKG2C/CD94 heterodimer or the CD94 homodimer.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Antibody clone number
- 131411
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Between Innate and Adaptive Immune Responses: NKG2A, NKG2C, and CD8⁺ T Cell Recognition of HLA-E Restricted Self-Peptides Acquired in the Absence of HLA-Ia.
Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo.
Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components.
Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil.
Natural killer cells in perinatally HIV-1-infected children exhibit less degranulation compared to HIV-1-exposed uninfected children and their expression of KIR2DL3, NKG2C, and NKp46 correlates with disease severity.
Pump WC, Kraemer T, Huyton T, Hò GT, Blasczyk R, Bade-Doeding C
International journal of molecular sciences 2019 Mar 22;20(6)
International journal of molecular sciences 2019 Mar 22;20(6)
Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo.
Gill US, Peppa D, Micco L, Singh HD, Carey I, Foster GR, Maini MK, Kennedy PT
PLoS pathogens 2016 Aug;12(8):e1005788
PLoS pathogens 2016 Aug;12(8):e1005788
Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbé C, Caillat-Zucman S
PLoS pathogens 2012 Jan;8(1):e1002486
PLoS pathogens 2012 Jan;8(1):e1002486
Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components.
Alici E, Sutlu T, Björkstrand B, Gilljam M, Stellan B, Nahi H, Quezada HC, Gahrton G, Ljunggren HG, Dilber MS
Blood 2008 Mar 15;111(6):3155-62
Blood 2008 Mar 15;111(6):3155-62
Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil.
Teixeira-Carvalho A, Fujiwara RT, Stemmy EJ, Olive D, Damsker JM, Loukas A, Corrêa-Oliveira R, Constant SL, Bethony JM
Infection and immunity 2008 Dec;76(12):5810-6
Infection and immunity 2008 Dec;76(12):5810-6
Natural killer cells in perinatally HIV-1-infected children exhibit less degranulation compared to HIV-1-exposed uninfected children and their expression of KIR2DL3, NKG2C, and NKp46 correlates with disease severity.
Ballan WM, Vu BA, Long BR, Loo CP, Michaëlsson J, Barbour JD, Lanier LL, Wiznia AA, Abadi J, Fennelly GJ, Rosenberg MG, Nixon DF
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 1;179(5):3362-70
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 1;179(5):3362-70
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of NKG2A/CD159a in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human NKG2A/CD159a APC-conjugated Mono-clonal Antibody (Catalog # FAB1059A) and Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody (Catalog # FAB2408P). Quadrant markers were set based on isotype control antibody staining (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.