ART1

ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008]

Description

ADP-ribosyltransferase 1

Tissue specificity

Group enriched (skeletal muscle, tongue)

Predicted location

Membrane

Protein family

CD markers
Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted membrane proteins

Chromosome

11 (3645128 - 3664416)

Ensembl ID

ENSG00000129744  (ver. 103.38)

Orthologs

Mouse Art1: ENSMUSG00000030996

UniProt

P52961

neXtProt

NX_P52961

Human splice variants
Mouse splice variants

Protein structure