CREBL2

gene product
cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq, Jul 2008]
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28 antibodies from 9 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Abnova Corporation
5 antibodies
LifeSpan BioSciences, Inc.
2 antibodies
antibodies-online
8 antibodies
Novus Biologicals
6 antibodies
Acris Antibodies GmbH
2 antibodies
Proteintech Group
1 antibody
Atlas Antibodies
1 antibody
RabMAbs
1 antibody
Creative Biomart
2 antibodies