DIMT1

The protein encoded by this gene is a methyltransferase that is responsible for dimethylation of adjacent adenosines near the 18S rRNA decoding site. The encoded protein is essential for ribosome biogenesis, although its catalytic activity is not involved in the process. The yeast ortholog of this protein functions in the cytoplasm while this protein functions in the nucleus. [provided by RefSeq, Jan 2017]

Description

DIMT1 rRNA methyltransferase and ribosome maturation factor

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Nucleoli, Nucleoli rim, Cytosol

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

5 (62347284 - 62403943)

Ensembl ID

ENSG00000086189  (ver. 103.38)

Orthologs

Mouse Dimt1: ENSMUSG00000021692

UniProt

Q9UNQ2

neXtProt

NX_Q9UNQ2

Human splice variants
Mouse splice variants

Protein structure