Tissue expression
Cell line expression
Protein structure
UBR1
Ubiquitin protein ligase E3 component n-recognin 1The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | ![]() |
2 references | Monoclonal |
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Proteintech Group | ![]() |
3 references | Polyclonal |
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antibodies-online | ![]() |
1 references | Monoclonal |
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Abnova Corporation | ![]() |
1 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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