BS8232

antibody from Bioworld Technology, Inc
Targeting: AIPL1 LCA4
Provider product page for BS8232
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8232 - Provider product page
Provider
Bioworld Technology, Inc
Product name
AIPL1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human AIPL1.
Description
The inherited blindness associated protein, aryl hydrocarbon receptor interacting protein-like 1 (AIPL1), interacts with the cell cycle regulator protein NUB1. AIPL1 is crucial for protein folding and stabilization, as well as for protein trafficking. It localizes to the nucleus or cytoplasm and is highly expressed in the pineal gland and the retina. In the retina, AIPL1 is expressed in both developing cone and rod photoreceptors, but it is restricted to rod photoreceptors in the adult human retina. Defects in the gene encoding for AIPL1 can cause Leber congenital amaurosis type IV, an early-onset, inherited autosomal recessive disorder that results in childhood blindness.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
AIPL1 protein structure - BS8232 shown in red.