abx003428

antibody from Abbexa

Targeting: GTPBP4 CRFG, FLJ10686, FLJ10690, NGB, NOG1

Western blot (Recommended by provider)

Antibody Data

Product number

abx003428

Provider

Abbexa

Product name

GTP Binding Protein 4 (GTPBP4) Antibody

Antibody type

Polyclonal

Description

GTPBP4 Antibody is a Rabbit Polyclonal antibody against GTPBP4. GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

> 1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.