Tissue expression
Cell line expression
Protein structure
PIK3C2G
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gammaThe protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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Affinity Biosciences | ![]() |
Polyclonal |
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Abnova Corporation | ![]() |
1 references | Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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