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Protein structure
TMPO
ThymopoietinLAP2, LEMD4, TP
Through alternative splicing, this gene encodes several distinct LEM domain containing protein isoforms. LEM domain proteins include inner nuclear membrane and intranuclear proteins, and are involved in a variety of cellular functions including gene expression, chromatin organization, and replication and cell cycle control. The encoded alpha isoform is broadly diffuse in the nucleus and contains a lamin binding domain, while the beta and gamma isoforms are localized to the nuclear membrane and contain an HDAC3 interaction domain. The distinct isoforms may compete with each other when acting to chaperone other proteins and regulate transcription. [provided by RefSeq, Aug 2019]
Top validated antibodies |
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| Atlas Antibodies |  HPA008150 |
1 references | Polyclonal |
WB
ICC
IHC
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| Proteintech Group | 14651-1-AP |
6 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 14651-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| Novus Biologicals | NBP1-87822 |
2 references | Polyclonal |
WB
ICC
IHC
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| NovoPro Bioscience Inc. | 112141 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
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