ABIN1673541

antibody from antibodies-online

Targeting: CD244 2B4, NAIL, NKR2B4, Nmrk, SLAMF4

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1673541

Provider

antibodies-online

Product name

anti-CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) (C-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence at the C-terminal of human CD244.Immunogen affinity purified.

Reactivity

Human

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.

Suzuki A, Yamada R, Kochi Y, Sawada T, Okada Y, Matsuda K, Kamatani Y, Mori M, Shimane K, Hirabayashi Y, Takahashi A, Tsunoda T, Miyatake A, Kubo M, Kamatani N, Nakamura Y, Yamamoto K
Nature genetics 2008 Oct;40(10):1224-9

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NK cell inhibitory receptors prevent tyrosine phosphorylation of the activation receptor 2B4 (CD244).

Watzl C, Stebbins CC, Long EO
Journal of immunology (Baltimore, Md. : 1950) 2000 Oct 1;165(7):3545-8

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Molecular characterization of a novel human natural killer cell receptor homologous to mouse 2B4.

Boles KS, Nakajima H, Colonna M, Chuang SS, Stepp SE, Bennett M, Kumar V, Mathew PA
Tissue antigens 1999 Jul;54(1):27-34

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2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48.

Brown MH, Boles K, van der Merwe PA, Kumar V, Mathew PA, Barclay AN
The Journal of experimental medicine 1998 Dec 7;188(11):2083-90