Tissue expression
Cell line expression
Protein structure
RRBP1
Ribosome binding protein 1ES/130, hES
This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq, Apr 2012]
Top validated antibodies |
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Atlas Antibodies | HPA009026 | 1 references | Polyclonal |
WB
ICC
IHC
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Proteintech Group | 22015-1-AP | 3 references | Polyclonal |
WB
EL
ICC
IHC
FC
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Invitrogen Antibodies | 22015-1-AP | Polyclonal |
WB
ICC
IHC
FC |
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GeneTex | GTX101844 | Polyclonal |
WB
ICC
IHC
|
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NSJ Bioreagents | RQ4954 | Polyclonal |
WB
ICC
IHC
FC |
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