MB2030

antibody from Bioworld Technology, Inc
Targeting: EIF4A1 DDX2A, EIF-4A, EIF4A
Provider product page for MB2030

Antibody data

Product number
MB2030 - Provider product page
Provider
Bioworld Technology, Inc
Product name
eIF4A1 Mouse monoclonal antibody
Antibody type
Monoclonal
Antigen
Recombinant full length Human eIF4A1.
Description
Mammalian eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that contains eIF4A, eIF4E and eIF4G, binds mRNA at a 5£ª-cap motif and recruits the 43S ribosomal preinitiation complex to the eligible transcript. Along with eIF4B, the eIF4F complex mediates the unwinding of mRNA secondary structure to facilitate ribosome association. eIF4E specifically interacts with the 5£ª cap, eIF4A(I,II) are bidirectional RNA helicases, and eIF4G(I,II) are scaffolding proteins which coordinate eIF4E, eIF4A, eIF3 and the 40S ribosome. Human eIF4AI (eIF4A, DDX2A) is a 406 amino acid protein that is 92.7% homologous to mouse eIF4AI. The promoter region of human eIF4A1 contains TATA and CAAT motifs and consensus binding sites to Sp1 and AP2.
Reactivity
Human, Mouse, Rat
Host
Mouse
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
EIF4A1 protein structure - MB2030 shown in red.