HUS1B

The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. [provided by RefSeq, Jul 2008]

Description

HUS1 checkpoint clamp component B

Tissue specificity

Tissue enhanced (testis)

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

6 (655939 - 656963)

Ensembl ID

ENSG00000188996  (ver. 103.38)

Orthologs

Mouse Hus1b: ENSMUSG00000076430

UniProt

Q8NHY5

neXtProt

NX_Q8NHY5

Human splice variants
Mouse splice variants

Protein structure