10043-2-AP

antibody from Proteintech Group

Targeting: RB1CC1 ATG17, Cc1, DRAGOU14, FIP200, KIAA0203, PPP1R131

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

10043-2-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#10043-2-AP, RRID:AB_2253571

Product name

RB1CC1 antibody

Antibody type

Polyclonal

Description

KD/KO validated RB1CC1 antibody (Cat. #10043-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Alternative mitochondrial quality control mediated by extracellular release.

Choong CJ, Okuno T, Ikenaka K, Baba K, Hayakawa H, Koike M, Yokota M, Doi J, Kakuda K, Takeuchi T, Kuma A, Nakamura S, Nagai Y, Nagano S, Yoshimori T, Mochizuki H
Autophagy 2021 Oct;17(10):2962-2974

---

Repairing and Analgesic Effects of Umbilical Cord Mesenchymal Stem Cell Transplantation in Mice with Spinal Cord Injury.

Wu LL, Pan XM, Chen HH, Fu XY, Jiang J, Ding MX
BioMed research international 2020;2020:7650354

---

Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms.

Wandel MP, Kim BH, Park ES, Boyle KB, Nayak K, Lagrange B, Herod A, Henry T, Zilbauer M, Rohde J, MacMicking JD, Randow F
Nature immunology 2020 Aug;21(8):880-891

---

The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria.

Ravenhill BJ, Boyle KB, von Muhlinen N, Ellison CJ, Masson GR, Otten EG, Foeglein A, Williams R, Randow F
Molecular cell 2019 Apr 18;74(2):320-329.e6

---

Accumulation of undegraded autophagosomes by expression of dominant-negative STX17 (syntaxin 17) mutants.

Uematsu M, Nishimura T, Sakamaki Y, Yamamoto H, Mizushima N
Autophagy 2017 Aug 3;13(8):1452-1464

---

ATM functions at the peroxisome to induce pexophagy in response to ROS.

Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL
Nature cell biology 2015 Oct;17(10):1259-1269

---

Structure of the Atg101-Atg13 complex reveals essential roles of Atg101 in autophagy initiation.

Suzuki H, Kaizuka T, Mizushima N, Noda NN
Nature structural & molecular biology 2015 Jul;22(7):572-80

---

Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis.

Wen J, Yeo S, Wang C, Chen S, Sun S, Haas MA, Tu W, Jin F, Guan JL
Breast cancer research and treatment 2015 Feb;149(3):619-29

---

Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels.

Zhong Y, Morris DH, Jin L, Patel MS, Karunakaran SK, Fu YJ, Matuszak EA, Weiss HL, Chait BT, Wang QJ
The Journal of biological chemistry 2014 Sep 19;289(38):26021-26037

---

Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment.

Ge L, Zhang M, Schekman R
eLife 2014 Nov 28;3:e04135

---

Identification of miR-133b and RB1CC1 as independent predictors for biochemical recurrence and potential therapeutic targets for prostate cancer.

Li X, Wan X, Chen H, Yang S, Liu Y, Mo W, Meng D, Du W, Huang Y, Wu H, Wang J, Li T, Li Y
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 May 1;20(9):2312-25

---

p62/SQSTM1 synergizes with autophagy for tumor growth in vivo.

Wei H, Wang C, Croce CM, Guan JL
Genes & development 2014 Jun 1;28(11):1204-16

---

Autophagy deficiency by hepatic FIP200 deletion uncouples steatosis from liver injury in NAFLD.

Ma D, Molusky MM, Song J, Hu CR, Fang F, Rui C, Mathew AV, Pennathur S, Liu F, Cheng JX, Guan JL, Lin JD
Molecular endocrinology (Baltimore, Md.) 2013 Oct;27(10):1643-54

---

The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-β signaling.

Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G
Developmental biology 2013 May 15;377(2):415-27

---

Noncanonical autophagy promotes the visual cycle.

Kim JY, Zhao H, Martinez J, Doggett TA, Kolesnikov AV, Tang PH, Ablonczy Z, Chan CC, Zhou Z, Green DR, Ferguson TA
Cell 2013 Jul 18;154(2):365-76

---

Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.

Gammoh N, Florey O, Overholtzer M, Jiang X
Nature structural & molecular biology 2013 Feb;20(2):144-9

---

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

Nazio F, Strappazzon F, Antonioli M, Bielli P, Cianfanelli V, Bordi M, Gretzmeier C, Dengjel J, Piacentini M, Fimia GM, Cecconi F
Nature cell biology 2013 Apr;15(4):406-16

---

Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity.

Wang D, Olman MA, Stewart J Jr, Tipps R, Huang P, Sanders PW, Toline E, Prayson RA, Lee J, Weil RJ, Palmer CA, Gillespie GY, Liu WM, Pieper RO, Guan JL, Gladson CL
PloS one 2011;6(5):e19629

---

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.

Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X
The Journal of biological chemistry 2009 May 1;284(18):12297-305