BS8000

antibody from Bioworld Technology, Inc

Targeting: CDYL CDYL1, DKFZP586C1622

Immunohistochemistry

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Validation data

Product number: BS8000 - Provider product page
Provider: Bioworld Technology, Inc
Product name: CDYL polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human CDYL.
Description: CDY, a gene family expressed exclusively in the testis, localizes to a region of the Y chromosome frequently deleted in infertile males. CDY protein contains two functional domains, an N-terminal chromodomain, possibly functioning in heterochromatin interactions, and also a C-terminal domain which resembles enoyl-CoA-isomerase, a protein involved in fatty acid oxidation. Furthermore, CDY acts as a histone acetyltransferase, with strong preference for histone H4, a process required for the histone to proamine transition in spermatogenesis, consistent with the association with male infertility. Chromodomain Y-like protein (CDYL) is a related ubiquitous nuclear protein expressed at moderate levels in most tissues. The gene encoding for the CDYL protein localizes to chromosome 6p25.1.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

CDYL protein structure - BS8000 shown in red.