ADAMTSL1

This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]

Description

ADAMTS like 1

Tissue specificity

Tissue enhanced (endometrium)

Subcell location

Vesicles

Predicted location

Intracellular, Secreted in other tissues

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

9 (17906563 - 18910950)

Ensembl ID

ENSG00000178031  (ver. 103.38)

Orthologs

Mouse Adamtsl1: ENSMUSG00000066113

UniProt

Q8N6G6

neXtProt

NX_Q8N6G6

Human splice variants
Mouse splice variants

Protein structure