Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS60296 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- IFN Àß polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human IFN-Àß.
- Description
- The genes encoding type I interferons (IFNs), which include 14 IFN-Ï« genes, 1 IFN-ÉÇ gene, 1 IFN-Àß (also known as IFN-Ï« II1) gene, and a number of IFN-Àß pseudogenes, are clustered on human chromosome 9. Interferons-Ï« and -ÉÇ are cytokines that are widely known to induce potent anti-viral activity. IFN-Ï« and -ÉÇ exert a variety of other biological effects, including anti-tumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-Àß is antigenically different from human IFN-Ï«, IFN-ÉÇ or IFN-ÎÛ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The Type I interferon receptor (IFN-Ï«R) interacts with IFN-Ï«, IFN-ÉÇ and IFN-Àß, and seems to be a multisubunit receptor.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of IFN-¦Ø pAb at 1:500 dilutionLane1:HEK293T cell lysateLane2:NIH-3T3 cell lysateLane3:H9C2 cell lysate