CABT-B11112

antibody from Creative Diagnostics

Targeting: NECTIN4 LNIR, nectin-4, PRR4, PVRL4

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-B11112

Provider

Creative Diagnostics

Product name

Mouse anti-Human PVRL4 monoclonal antibody, clone 2E8

Antibody type

Monoclonal

Description

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgM

Antibody clone number

2.00E+08

Vial size

200 _l

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.