PATZ1

gene product
dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG
The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008]
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52 antibodies from 13 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
5 antibodies
GeneTex
2 antibodies
Thermo Fisher Scientific Pierce
2 antibodies
antibodies-online
22 antibodies
Abnova Corporation
2 antibodies
Aviva Systems Biology
3 antibodies
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
3 antibodies
Biorbyt
2 antibodies
Bioss
1 antibody
Creative Biomart
5 antibodies
Sigma-Aldrich
3 antibodies
United States Biological
1 antibody