AMM01936G

antibody from Leading Biology
Targeting: TOPORS LUN, RP31, TP53BPL
Provider product page for AMM01936G
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
AMM01936G - Provider product page
Provider
Leading Biology
Product name
TOPORS Antibody (clone 5G11)
Antibody type
Monoclonal
Description
Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage- induced cell death through IKBKE sumoylation.
Reactivity
Human
Host
Mouse
Antibody clone number
5G11
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
TOPORS protein structure - AMM01936G shown in red.