Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM01936G - Provider product page
- Provider
- Leading Biology
- Product name
- TOPORS Antibody (clone 5G11)
- Antibody type
- Monoclonal
- Description
- Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage- induced cell death through IKBKE sumoylation.
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- 5G11
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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