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Protein structure
SETMAR
SET domain and mariner transposase fusion genemetnase
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Top validated antibodies |
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| Novus Biologicals |  NB100-1142 |
2 references | Polyclonal |
WB
EL
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| Invitrogen Antibodies | 25814-1-AP |
Polyclonal |
WB
IP
OA
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| NovoPro Bioscience Inc. | 115132 |
Polyclonal |
WB
EL
IP
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| Proteintech Group | 25814-1-AP |
Polyclonal |
WB
EL
IP
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| antibodies-online | ABIN184884 |
1 references | Polyclonal |
WB
EL
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