Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- H00079733-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00079733-M01, RRID:AB_2262103
- Product name
- Mouse Monoclonal E2F8 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. E2F8 - E2F transcription factor 8
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo.
Unbiased transcriptome signature of in vivo cell proliferation reveals pro- and antiproliferative gene networks.
E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1.
E2F8 contributes to human hepatocellular carcinoma via regulating cell proliferation.
DNA-damage response control of E2F7 and E2F8.
Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development.
de Bruin A, A Cornelissen PW, Kirchmaier BC, Mokry M, Iich E, Nirmala E, Liang KH, D Végh AM, Scholman KT, Groot Koerkamp MJ, Holstege FC, Cuppen E, Schulte-Merker S, Bakker WJ
Nucleic acids research 2016 May 5;44(8):3549-66
Nucleic acids research 2016 May 5;44(8):3549-66
Unbiased transcriptome signature of in vivo cell proliferation reveals pro- and antiproliferative gene networks.
Cohen M, Vecsler M, Liberzon A, Noach M, Zlotorynski E, Tzur A
Cell cycle (Georgetown, Tex.) 2013 Sep 15;12(18):2992-3000
Cell cycle (Georgetown, Tex.) 2013 Sep 15;12(18):2992-3000
E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1.
Weijts BG, Bakker WJ, Cornelissen PW, Liang KH, Schaftenaar FH, Westendorp B, de Wolf CA, Paciejewska M, Scheele CL, Kent L, Leone G, Schulte-Merker S, de Bruin A
The EMBO journal 2012 Oct 3;31(19):3871-84
The EMBO journal 2012 Oct 3;31(19):3871-84
E2F8 contributes to human hepatocellular carcinoma via regulating cell proliferation.
Deng Q, Wang Q, Zong WY, Zheng DL, Wen YX, Wang KS, Teng XM, Zhang X, Huang J, Han ZG
Cancer research 2010 Jan 15;70(2):782-91
Cancer research 2010 Jan 15;70(2):782-91
DNA-damage response control of E2F7 and E2F8.
Zalmas LP, Zhao X, Graham AL, Fisher R, Reilly C, Coutts AS, La Thangue NB
EMBO reports 2008 Mar;9(3):252-9
EMBO reports 2008 Mar;9(3):252-9
Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development.
Li J, Ran C, Li E, Gordon F, Comstock G, Siddiqui H, Cleghorn W, Chen HZ, Kornacker K, Liu CG, Pandit SK, Khanizadeh M, Weinstein M, Leone G, de Bruin A
Developmental cell 2008 Jan;14(1):62-75
Developmental cell 2008 Jan;14(1):62-75
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: E2F8 Antibody (3E9-2F5) [H00079733-M01] - Western Blot detection against Immunogen (73.15 KDa) .