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- Product number
- ABIN394269 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-E2F Transcription Factor 8 (E2F8) (AA 1-432) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-432
- Isotype
- IgG
- Antibody clone number
- S1
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references E2F8 contributes to human hepatocellular carcinoma via regulating cell proliferation.
DNA-damage response control of E2F7 and E2F8.
Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription.
Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation.
E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7.
Deng Q, Wang Q, Zong WY, Zheng DL, Wen YX, Wang KS, Teng XM, Zhang X, Huang J, Han ZG
Cancer research 2010 Jan 15;70(2):782-91
Cancer research 2010 Jan 15;70(2):782-91
DNA-damage response control of E2F7 and E2F8.
Zalmas LP, Zhao X, Graham AL, Fisher R, Reilly C, Coutts AS, La Thangue NB
EMBO reports 2008 Mar;9(3):252-9
EMBO reports 2008 Mar;9(3):252-9
Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription.
Christensen J, Cloos P, Toftegaard U, Klinkenberg D, Bracken AP, Trinh E, Heeran M, Di Stefano L, Helin K
Nucleic acids research 2005;33(17):5458-70
Nucleic acids research 2005;33(17):5458-70
Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation.
Maiti B, Li J, de Bruin A, Gordon F, Timmers C, Opavsky R, Patil K, Tuttle J, Cleghorn W, Leone G
The Journal of biological chemistry 2005 May 6;280(18):18211-20
The Journal of biological chemistry 2005 May 6;280(18):18211-20
E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7.
Logan N, Graham A, Zhao X, Fisher R, Maiti B, Leone G, La Thangue NB
Oncogene 2005 Jul 21;24(31):5000-4
Oncogene 2005 Jul 21;24(31):5000-4
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