MAB8508

antibody from Abnova Corporation

Targeting: ABRAXAS1 ABRA1, ABRAXAS, CCDC98, FAM175A, FLJ13614

No application information provided.

Antibody Data

Product number

MAB8508

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB8508, RRID:AB_10721494

Product name

FAM175A monoclonal antibody, clone ABRA1-01

Antibody type

Monoclonal

Description

Mouse monoclonal antibody raised against partial recombinant FAM175A.

Isotype

IgG

Antibody clone number

ABRA1-01

Storage

Store at 4°C. Do not freeze.

References

Submitted references

Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function.

Nikkilä J, Coleman KA, Morrissey D, Pylkäs K, Erkko H, Messick TE, Karppinen SM, Amelina A, Winqvist R, Greenberg RA
Oncogene 2009 Apr 23;28(16):1843-52

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Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.

Wang B, Matsuoka S, Ballif BA, Zhang D, Smogorzewska A, Gygi SP, Elledge SJ
Science (New York, N.Y.) 2007 May 25;316(5828):1194-8

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Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage.

Wang B, Elledge SJ
Proceedings of the National Academy of Sciences of the United States of America 2007 Dec 26;104(52):20759-63

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CCDC98 targets BRCA1 to DNA damage sites.

Liu Z, Wu J, Yu X
Nature structural & molecular biology 2007 Aug;14(8):716-20