FNab00139

antibody from FineTest Biotech

Targeting: ADAM17 CD156B, cSVP, TACE

Western blot

ELISA

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: FNab00139 - Provider product page
Provider: FineTest Biotech
Product name: ADAM17-Specific antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: The ADAMs(A Disintegrin And Metalloprotease) are multidomain transmembrane proteins. One of the first ADAMs implicated in membrane shedding is ADAM-17, which is shown to release the active form of tumor necrosis factor(TNF)-a from its precursor(PMID:18238782). ADAM17 is also named as CSVP, TACE. The full length protein has 9 glycosylation sites, a signal peptide, propeptide and 2 isoforms produced by alternative splicing.The 120-kDa form of ADAM-17 is expressed more frequently and at higher levels in primary breast carcinomas compared with normal breast tissue(PMID:17438092). This antibody is specific to ADAM17.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: ADAM metallopeptidase domain 17
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ADAM17 protein structure - FNab00139 shown in red.