Tissue expression
Cell line expression
Protein structure
IRS2
Insulin receptor substrate 2This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
LSBio | ![]() |
Polyclonal |
|
||
NSJ Bioreagents | ![]() |
Polyclonal |
|
||
Proteintech Group | ![]() |
10 references | Polyclonal |
|
|
Biorbyt | ![]() |
Polyclonal |
|
||
NovoPro Bioscience Inc. | ![]() |
Polyclonal |
|