FNab07535

antibody from FineTest Biotech

Targeting: RUNX1T1 AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2

Western blot

ELISA

Immunohistochemistry

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Validation data

Product number: FNab07535 - Provider product page
Provider: FineTest Biotech
Product name: RUNX1T1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes(PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner(PubMed:23251453). Can repress transactivation mediated by TCF12(PubMed:16803958). Acts as a negative regulator of adipogenesis(By similarity). The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal(PubMed:23812588).
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: runt-related transcription factor 1 ; translocated to, 1(cyclin D-relat ed)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

RUNX1T1 protein structure - FNab07535 shown in red.