27266-1-AP

antibody from Proteintech Group

Targeting: KMT2D ALR, CAGL114, MLL2, MLL4, TNRC21

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

27266-1-AP

Provider

Proteintech Group

Product name

KMT2D antibody

Antibody type

Polyclonal

Description

KD/KO validated KMT2D antibody (Cat. #27266-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Pseudogene ACTBP2 increases blood-brain barrier permeability by promoting KHDRBS2 transcription through recruitment of KMT2D/WDR5 in Aβ_1-42 microenvironment.

Liu Q, Liu X, Zhao D, Ruan X, Su R, Shang X, Wang D, Yang C, Xue Y
Cell death discovery 2021 Jun 14;7(1):142

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RNF213 gene mutation in circulating tumor DNA detected by targeted next-generation sequencing in the assisted discrimination of early-stage lung cancer from pulmonary nodules.

Jiang N, Zhou J, Zhang W, Li P, Liu Y, Shi H, Zhang C, Wang Y, Zhou C, Peng C, Zhang W, Hao Y, Sun Q, Li Y, Zhao X
Thoracic cancer 2021 Jan;12(2):181-193

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Histone 3 lysine-27 demethylase KDM6A coordinates with KMT2B to play an oncogenic role in NSCLC by regulating H3K4me3.

Leng X, Wang J, An N, Wang X, Sun Y, Chen Z
Oncogene 2020 Oct;39(41):6468-6479

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KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma.

Li SS, Jiang WL, Xiao WQ, Li K, Zhang YF, Guo XY, Dai YQ, Zhao QY, Jiang MJ, Lu ZJ, Wan R
World journal of gastrointestinal oncology 2019 Aug 15;11(8):599-621