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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Immunohistochemistry [5]
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- Product number
- NBP1-89123 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-89123, RRID:AB_11012029
- Product name
- Rabbit Polyclonal KMT2D Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human KMT2D antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.
Zhang J, Dominguez-Sola D, Hussein S, Lee JE, Holmes AB, Bansal M, Vlasevska S, Mo T, Tang H, Basso K, Ge K, Dalla-Favera R, Pasqualucci L
Nature medicine 2015 Oct;21(10):1190-8
Nature medicine 2015 Oct;21(10):1190-8
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.
Dubuc AM, Remke M, Korshunov A, Northcott PA, Zhan SH, Mendez-Lago M, Kool M, Jones DT, Unterberger A, Morrissy AS, Shih D, Peacock J, Ramaswamy V, Rolider A, Wang X, Witt H, Hielscher T, Hawkins C, Vibhakar R, Croul S, Rutka JT, Weiss WA, Jones SJ, Eberhart CG, Marra MA, Pfister SM, Taylor MD
Acta neuropathologica 2013 Mar;125(3):373-84
Acta neuropathologica 2013 Mar;125(3):373-84
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human cervix, uterine shows weak nuclear positivity in squamous epithelial cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human pancreas shows weak nuclear positivity in exocrine glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human rectum shows moderate nuclear positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human testis shows moderate nuclear positivity in cells in seminiferous ducts.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: KMT2D Antibody [NBP1-89123] - Staining of human endometrium shows moderate nuclear positivity in glandular cells.
