13365-1-AP
antibody from Proteintech Group
Targeting: NAT10
FLJ10774, FLJ12179, hALP, KIAA1709, Kre33, NET43
Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
Reference
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- Product number
- 13365-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13365-1-AP, RRID:AB_2148944
- Product name
- NAT10 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NAT10 antibody (Cat. #13365-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NAT10-Mediated N4-Acetylcytidine of RNA Contributes to Post-transcriptional Regulation of Mouse Oocyte Maturation in vitro.
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Prognostic and Immunological Role of mRNA ac4C Regulator NAT10 in Pan-Cancer: New Territory for Cancer Research?
Multiple Omics Integration Reveals Key Circular RNAs in Hepatocellular Carcinoma.
Single-Cell RNA-Sequencing Reveals the Breadth of Osteoblast Heterogeneity.
ac4C acetylation of RUNX2 catalyzed by NAT10 spurs osteogenesis of BMSCs and prevents ovariectomy-induced bone loss.
Knee loading repairs osteoporotic osteoarthritis by relieving abnormal remodeling of subchondral bone via Wnt/β-catenin signaling.
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.
CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation.
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
RAB35 depletion affects spindle formation and actin-based spindle migration in mouse oocyte meiosis.
Rab23/Kif17 regulate meiotic progression in oocytes by modulating tubulin acetylation and actin dynamics.
Kif18a regulates Sirt2-mediated tubulin acetylation for spindle organization during mouse oocyte meiosis.
Acetylation of Cytidine in mRNA Promotes Translation Efficiency.
Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome.
Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.
RCCD1 depletion attenuates TGF-β-induced EMT and cell migration by stabilizing cytoskeletal microtubules in NSCLC cells.
Chemical inhibition of NAT10 corrects defects of laminopathic cells.
Xiang Y, Zhou C, Zeng Y, Guo Q, Huang J, Wu T, Liu J, Liang Q, Zeng H, Liang X
Frontiers in cell and developmental biology 2021;9:704341
Frontiers in cell and developmental biology 2021;9:704341
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Dong XH, Zhang MZ, Lai CZ, Li CC, Du L, Song GD, Zong XL, Jin XL
American journal of translational research 2021;13(10):11255-11270
American journal of translational research 2021;13(10):11255-11270
Prognostic and Immunological Role of mRNA ac4C Regulator NAT10 in Pan-Cancer: New Territory for Cancer Research?
Yang C, Wu T, Zhang J, Liu J, Zhao K, Sun W, Zhou X, Kong X, Shi J
Frontiers in oncology 2021;11:630417
Frontiers in oncology 2021;11:630417
Multiple Omics Integration Reveals Key Circular RNAs in Hepatocellular Carcinoma.
Huang ZL, Huang XY, Huang J, Huang XY, Xu YH, Zhou J, Tang ZY
Frontiers in oncology 2021;11:621353
Frontiers in oncology 2021;11:621353
Single-Cell RNA-Sequencing Reveals the Breadth of Osteoblast Heterogeneity.
Yoshioka H, Okita S, Nakano M, Minamizaki T, Nubukiyo A, Sotomaru Y, Bonnelye E, Kozai K, Tanimoto K, Aubin JE, Yoshiko Y
JBMR plus 2021 Jun;5(6):e10496
JBMR plus 2021 Jun;5(6):e10496
ac4C acetylation of RUNX2 catalyzed by NAT10 spurs osteogenesis of BMSCs and prevents ovariectomy-induced bone loss.
Yang W, Li HY, Wu YF, Mi RJ, Liu WZ, Shen X, Lu YX, Jiang YH, Ma MJ, Shen HY
Molecular therapy. Nucleic acids 2021 Dec 3;26:135-147
Molecular therapy. Nucleic acids 2021 Dec 3;26:135-147
Knee loading repairs osteoporotic osteoarthritis by relieving abnormal remodeling of subchondral bone via Wnt/β-catenin signaling.
Zheng W, Ding B, Li X, Liu D, Yokota H, Zhang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):3399-3412
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):3399-3412
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.
Tsai K, Jaguva Vasudevan AA, Martinez Campos C, Emery A, Swanstrom R, Cullen BR
Cell host & microbe 2020 Aug 12;28(2):306-312.e6
Cell host & microbe 2020 Aug 12;28(2):306-312.e6
CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation.
Wang T, Zou Y, Huang N, Teng J, Chen J
Cell reports 2019 Nov 12;29(7):2078-2091.e5
Cell reports 2019 Nov 12;29(7):2078-2091.e5
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Shi A, Heinayati A, Bao D, Liu H, Ding X, Tong X, Wang L, Wang B, Qin H
Stem cell research & therapy 2019 Jun 13;10(1):172
Stem cell research & therapy 2019 Jun 13;10(1):172
RAB35 depletion affects spindle formation and actin-based spindle migration in mouse oocyte meiosis.
Zhang Y, Wan X, Wang HH, Pan MH, Pan ZN, Sun SC
Molecular human reproduction 2019 Jul 1;25(7):359-372
Molecular human reproduction 2019 Jul 1;25(7):359-372
Rab23/Kif17 regulate meiotic progression in oocytes by modulating tubulin acetylation and actin dynamics.
Wang HH, Zhang Y, Tang F, Pan MH, Wan X, Li XH, Sun SC
Development (Cambridge, England) 2019 Feb 4;146(3)
Development (Cambridge, England) 2019 Feb 4;146(3)
Kif18a regulates Sirt2-mediated tubulin acetylation for spindle organization during mouse oocyte meiosis.
Tang F, Pan MH, Wan X, Lu Y, Zhang Y, Sun SC
Cell division 2018;13:9
Cell division 2018;13:9
Acetylation of Cytidine in mRNA Promotes Translation Efficiency.
Arango D, Sturgill D, Alhusaini N, Dillman AA, Sweet TJ, Hanson G, Hosogane M, Sinclair WR, Nanan KK, Mandler MD, Fox SD, Zengeya TT, Andresson T, Meier JL, Coller J, Oberdoerffer S
Cell 2018 Dec 13;175(7):1872-1886.e24
Cell 2018 Dec 13;175(7):1872-1886.e24
Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome.
Balmus G, Larrieu D, Barros AC, Collins C, Abrudan M, Demir M, Geisler NJ, Lelliott CJ, White JK, Karp NA, Atkinson J, Kirton A, Jacobsen M, Clift D, Rodriguez R, Sanger Mouse Genetics Project., Adams DJ, Jackson SP
Nature communications 2018 Apr 27;9(1):1700
Nature communications 2018 Apr 27;9(1):1700
Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.
Hicks JA, Li L, Matsui M, Chu Y, Volkov O, Johnson KC, Corey DR
Cell reports 2017 Aug 15;20(7):1543-1552
Cell reports 2017 Aug 15;20(7):1543-1552
RCCD1 depletion attenuates TGF-β-induced EMT and cell migration by stabilizing cytoskeletal microtubules in NSCLC cells.
Wu J, He Z, Yang XM, Li KL, Wang DL, Sun FL
Cancer letters 2017 Aug 1;400:18-29
Cancer letters 2017 Aug 1;400:18-29
Chemical inhibition of NAT10 corrects defects of laminopathic cells.
Larrieu D, Britton S, Demir M, Rodriguez R, Jackson SP
Science (New York, N.Y.) 2014 May 2;344(6183):527-32
Science (New York, N.Y.) 2014 May 2;344(6183):527-32
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 13365-1-AP(NAT10 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using NAT10 antibody 13365-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line