Tissue expression
Cell line expression
Protein structure
TMED10
Transmembrane p24 trafficking protein 10p23, P24(DELTA), p24d1, p24delta1, TMP21
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 15199-1-AP | 8 references | Polyclonal |
WB
EL
ICC
IHC |
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Atlas Antibodies | HPA047139 | Polyclonal |
WB
ICC
IHC
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antibodies-online | ABIN500992 | 4 references | Polyclonal |
WB
EL
IHC
|
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Novus Biologicals | NB100-58962 | 1 references | Polyclonal |
EL
ICC
FC
|
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Boster Biological Technology | A07234 | Polyclonal |
WB
EL
ICC
IHC |
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Recommended by provider